Vinpocetine Modulates Metabolic Activity and Function during Retinal

1 ISCHEMIA 2 3 Lisa Nivison-Smith, Brendan J. O’Brien, Mai Truong, Cindy X. Guo, Michael Kalloniatis and 4 Monica L. Acosta 5 6 School of Optometry and Vision Science, University of New South Wales, Sydney, 2052, Australia, 7 Department of Optometry and Vision Science, University of Auckland, 1023, New Zealand, 8 Centre for Eye Health, University of New South Wales, Sydney, 2052, Australia, 9 New Zealand National Eye Centre, University of Auckland, Auckland, 1023, New Zealand. 10 11 Correspondence 12 Dr. Monica Acosta 13 Department of Optometry and Vision Science, University of Auckland, Auckland, 1023, New Zealand. 14 Phone: +64 (0) 9 923 6069 15 E-mail: [email protected] 16 17 Abbreviations 18 LDH, lactate dehydrogenase; ERG, electroretinogram; 19 20 Number of pages: 23 21 Number of figures: 8 22 Word count: Total: 5056, Abstract: 206, Introduction: 339, Discussion: 888 23 24 Grant information 25 This work was supported in part by an Auckland Medical Research Foundation (AMRF #1109007), the 26 New Zealand Optometric Vision Research Foundation (NZOVRF #3620315) and research grants from 27 the National Health and Medical Research Council of Australia (#1009342) and the University of New 28 South Wales (#PS35430). 29 30 Running title: Vinpocetine alters metabolism in retinal ischemia 31 32 Articles in PresS. Am J Physiol Cell Physiol (February 18, 2015). doi:10.1152/ajpcell.00291.2014